Malignant lymphoma, also known as reticulosarcoma or primary bone non-Hodgkin lymphoma, is a tumor composed of malignant lymphocytes that forms expansive lesions within the bone. It may manifest as a primary tumor or as a secondary condition resulting from systemic lymphoma or extranodal lymphoma originating in other sites. The condition typically occurs in individuals aged 40 to 60 years. Pain and the presence of a mass are the predominant clinical features, and pathological fractures are commonly observed. X-ray imaging often shows extensive, irregular lytic bone lesions, sometimes described as the "melting ice sign," while periosteal reaction is rare.
Treatment
Radiotherapy and chemotherapy are the main treatment modalities, with surgery serving as an adjunct when necessary. Surgical approaches include limb-sparing procedures or amputation, and the prognosis is generally favorable.